TWO-STEP ACTIVATION MECHANISM OF THE CLPB DISAGGREGASE FOR SEQUENTIAL SUBSTRATE THREADING BY THE MAIN ATPASE MOTOR

Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor

Summary: AAA+ proteins form asymmetric Generations hexameric rings that hydrolyze ATP and thread substrate proteins through a central channel via mobile substrate-binding pore loops.Understanding how ATPase and threading activities are regulated and intertwined is key to understanding the AAA+ protein mechanism.We studied the disaggregase ClpB, whi

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Gene flow in a national cross-breeding beef population

Future progress in genetic improvement and the monitoring of genetic resources in beef cattle requires a detailed understanding of the population under selection.This study examines the gene flow in the UK beef population with an uncommon breeding structure involving interaction between the beef and dairy populations.British Cattle Movement Service

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The Effectiveness of the Addition of Platelet-Rich Fibrin to Bovine Xenografts in Sinus and Bone Ridge Augmentation: A Systematic Review

Dental implants sometimes need bone augmentation to recreate an adequate bone height and volume.Numerous bone augmentation techniques have been described, and, currently, the most commonly used bone graft procedure is xenografts with deproteinized bovine bone mineral (DBBM).The addition of platelet-rich fibrin (PRF) to DBBM has already shown better

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